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10.7759/cureus.73335 106 Losada-BarreiroS.CelikS.Sezgin-BayindirZ.Bravo-FernandezS.Bravo-DiazC

The novelty of this review lies in its comprehensive approach that brings together biomarkers of oxidative stress, inflammation, and genetic/epigenetic regulation within a clinically oriented multi-omics and an artificial intelligence (AI)-guided framework

Frequency of Use Remember that coffee enemas are not approved for any of their purported benefits and evidence of their effectiveness is generally lacking

Am J Clin Nutr 89:2025S-2039S

The overexpression of miR-21 and miR-433 and the downregulation of miR-590 in UC patients are significantly related to TGF- signaling pathway activity and can be used as potential targets for UC treatment